Systemic Symptoms & Conditions
Now let’s discuss the potential systemic symptoms and health conditions associated with leaky gut. It is important to note that these non-digestive signs and symptoms may have many possible explanations. If you are experiencing any of these symptoms, it is important to...
Intestinal Symptoms & Conditions
Leaky gut is associated with an array of symptoms and health conditions. It’s important to initially consult with your doctor about your symptoms and health issues to exclude other potential diagnoses. With that in mind, let’s delve into some intestinal symptoms that...
Stress and Sleep Deprivation
Stress Chronic stress is a persistent and ongoing state of stress that can have a negative impact on many aspects of health, including gut health. Chronic stress can contribute to the development of leaky gut by disrupting the balance of the gut...
Dietary Factors
One of the primary causes of leaky gut is an unhealthy diet, particularly one high in processed foods, refined sugars, and artificial additives. Excess consumption of these foods may directly or indirectly impact the gut barrier, gut microbiota, and inflammation levels. Don’t...
Infections and Drugs
Infections and certain drugs can contribute to the development of leaky gut by altering the gut microbiota, increasing inflammation, and disrupting the tight junctions. The primary course of action should be collaborating with your healthcare provider to effectively treat the infection. Post-treatment,...
Chronic Inflammation
Chronic inflammation is a prolonged, low-grade immune response that often goes unnoticed, but can precipitate numerous health problems, including the onset of Leaky Gut Syndrome. Let’s discuss the scientific principles behind chronic inflammation, emphasizing its role in amplifying gut permeability, and detailing...
Intestinal Epithelial Cells & Tight Junctions
Intestinal Epithelial Cells The intestinal epithelial cells (IECs) play a critical role in the maintenance of gut barrier function. These cells line the intestinal wall and form a physical and functional barrier between the gut lumen and the bloodstream, regulating the passage...
Structure and Function of the Gut Barrier
The gut barrier is the first line of defense against foreign substances and pathogens that enter the body through the gastrointestinal tract. It is a complex system composed of physical, chemical, and biological components that work together to protect the body while...
Gut-Associated Lymphoid Tissue
The gut is home to the largest collection of immune cells in the body. The gut-associated lymphoid tissue (GALT) is the collection of immune cells and tissues that are located in the gastrointestinal tract. It is estimated that approximately 70% of the...
Anti-Nutrients
Anti-nutrients are compounds found in plant-based foods that can interfere with the absorption of certain nutrients, leading to reduced bioavailability and potential nutrient deficiencies. We’re not eliminating all anti-nutrients, as those foods have many other beneficial phytochemicals. It’s important to note which...