By Dr. Ryan Kneessi, ND — licensed naturopathic doctor in Maryland · Move Forward Natural Health, Odenton, MD (in-office and telehealth visits) · Last reviewed: October 9, 2026
Quick answer: Chronic stress keeps cortisol and adrenaline elevated, which disrupts sleep, digestion, mood and focus. Daily practices such as slow breathing, morning light and steady meals are the foundation. Calming nutrients such as L-theanine, magnesium, phosphatidylserine, lemon balm and saffron, along with adaptogens like ashwagandha and rhodiola, can help the nervous system settle.
How stress affects the body
- Poor sleep and racing thoughts
- Digestive changes
- Cravings and blood sugar swings
- Muscle tension and headaches
- Lower immune resilience
Daily practices that lower stress hormones
- Slow breathing, such as box breathing or 4-7-8 breathing, twice a day
- Morning sunlight to set your cortisol rhythm
- Regular meals with protein
- An evening wind-down routine, such as an Epsom salt bath
- Limiting caffeine after noon
Calming nutrients and herbs
- L-theanine: promotes relaxed focus; pairs well with morning coffee
- Magnesium glycinate: supports calm and sleep
- Phosphatidylserine: may help quiet evening racing thoughts
- Lemon balm, passionflower and valerian: traditional calming herbs
- Saffron: studied for anxiety and mood
- GABA and taurine: calming amino acids
- Adaptogens: such as ashwagandha, rhodiola and holy basil (see understanding adaptogens)
Amounts should be individualized. Calming supplements can add to the effects of sedatives, alcohol and some antidepressants. If you work with me, the products I use are in my Fullscript dispensary.
Is testing helpful?
For persistent stress symptoms, looking at cortisol patterns, thyroid, inflammation markers and blood sugar can help (see cortisol patterns). Functional labs are optional. They can be helpful in more complex cases, and in my practice they are available only to patients working 1-on-1 with me.
Stress and healthy aging
Long-term stress keeps the body in a state of alarm. It raises inflammation, strains mitochondria and is associated with shorter telomeres, the protective caps on chromosomes. Building calm into daily life is one of the most effective ways to protect how you age. Related: breathwork and natural sleep aids.
When to see a naturopathic doctor
- Stress is affecting your sleep, digestion or mood
- You feel anxious or on edge most days
- You want natural options alongside counseling or medication
- You take medications and want to use calming supplements safely
See a medical provider promptly If you are thinking about harming yourself, call or text 988 or call 911. Seek prompt care for chest pain or panic symptoms you have not had before.
Feeling stretched thin? Let us build a calmer baseline.
A free 15-minute consultation with Dr. Kneessi. No cost, no obligation. In-office in Odenton, MD or by telehealth.
Frequently asked questions
What is the best supplement for stress?
L-theanine and magnesium are gentle starting points. Adaptogens such as ashwagandha are well studied for stress.
Can I take L-theanine with coffee?
Yes. Many people find it smooths the jittery edge of caffeine.
How fast do calming supplements work?
Some, such as L-theanine, work within an hour. Adaptogens usually take a few weeks.
Are calming supplements safe with antidepressants?
Some can interact. Always check with your prescriber.
Sources
This article is for educational purposes only and is not medical advice. It does not replace an individual evaluation. Talk with your healthcare provider before starting supplements or changing medications, especially if you are pregnant, nursing, or managing a health condition.
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