By Dr. Ryan Kneessi, ND, a licensed naturopathic doctor at Move Forward Natural Health in Odenton, Maryland. Last reviewed October 11, 2026.
Healthy cholesterol and triglyceride balance is one part of long-term heart health, alongside blood pressure, blood sugar, movement and not smoking. Heart & Lipid Balance gathers well-researched nutrients that support healthy lipid metabolism and blood vessel health alongside diet and exercise.
Creating a Fullscript account is free, and you can look through every product before you decide anything.
The mechanisms this protocol supports
Cholesterol comes partly from what we absorb in the gut and partly from what the liver makes. Plant sterols compete with cholesterol for absorption, while plant polyphenols such as those from bergamot influence how the liver handles lipids.
Blood vessels are lined by the endothelium, which stays healthiest when oxidative stress and vascular inflammation are kept in balance. LDL particles that become oxidized are more likely to contribute to plaque, and stiffer blood vessels are one way the cardiovascular system shows aging.
Research has linked plant sterols with healthier LDL levels, omega-3 fats with lower triglycerides, and bergamot polyphenols with healthier lipid profiles in clinical trials. I left out red yeast rice on purpose because it contains a natural statin compound.
What is in the protocol
The exact products and directions are listed in the Fullscript plan, and here is what each one is commonly used to support.
- CholestePure from Pure Encapsulations provides plant sterols, which compete with cholesterol for absorption in the gut and are one of the most consistently studied nutritional approaches to LDL balance.
- ProOmega from Nordic Naturals provides the omega-3 fats EPA and DHA, which have been linked with lower triglyceride levels and a balanced inflammatory response in blood vessels.
- Super Ubiquinol CoQ10 with PQQ from Life Extension provides the active form of CoQ10, which supports mitochondrial energy in heart muscle, along with PQQ.
- BergaCor Plus from Xymogen combines bergamot polyphenols, which have been linked in clinical trials with healthier lipid levels, with amla, which supports endothelial function. When it is backordered, Bergamot BPF from Ortho Molecular Products may be used as an alternative.
Related protocols you may find helpful include Blood Pressure Support and Metabolic Flexibility.
How to use it thoughtfully
- Please talk with your provider before starting, especially if you take medications, are pregnant or nursing, or have a health condition.
- This page does not list amounts, so follow the label or the specific guidance your provider gives you.
- When you can, add one product at a time so it is easier to notice how you feel.
- Sleep, nourishing food, daily movement and stress care are the foundation, and supplements are meant to build on them.
- If you take a statin or another lipid medication, please talk with your prescriber before combining it with these products.
- Fish oil may affect bleeding, so tell your provider if you take a blood thinner or have surgery planned.
- Plant sterols can lower the absorption of some fat-soluble nutrients, so a varied, colorful diet matters.
- Statin medications lower the body’s own CoQ10 production, which is one reason CoQ10 is included here.
Frequently asked questions
Can I use this instead of a statin?
No, this protocol is nutritional support only, so please keep taking any prescribed medication and talk with your prescriber before making changes.
Why is red yeast rice not included?
Red yeast rice contains a natural statin compound, so I left it out to avoid unexpected overlap with prescription lipid medications.
Do I need an appointment to order these products?
No, you can create a free Fullscript account and order directly, although I always recommend checking with your own provider first, and a free 15-minute consult is available if you would like to talk it through.
Ready to see the full protocol?
Every product I use for this protocol is waiting for you in my Fullscript dispensary.
Not sure this is the right fit for you? Book a free 15-minute consult and we can talk it through together.
Educational purposes only. This page shares general information and is not medical advice. These statements have not been evaluated by the Food and Drug Administration, and these products are not intended to replace care from your own healthcare provider. Please talk with your provider before starting any supplement, especially if you take medications, are pregnant or nursing, or have a health condition.
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